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Comment Separation Processes

Single-use separator for the biopharmaceutical industry

By Mary Page Bailey and Gerald Ondrey |

The new kytero single-use separator (photo) is designed for obtaining fermentation solutions and cell cultures, and is equipped with the Westfalia Separator disk-stack technology for maximum yield, high separation efficiency and gentle product handling. The kytero combines the high performance of larger stainless-steel pharmaceutical centrifuges with the features and benefits offered by disposable separation. The mobile plug-and-produce unit also fits into any clean room. All elements in contact with the product, such as hoses and containers, are made of recyclable material and are replaced after use. This prevents any cross-contamination and ensures hygienic harvesting of the cells. The elimination of CIP (clean-in-place) and SIP (sterilize-in-place) also eliminates the cost of chemicals and water, especially water-for-injection (WFI). In addition, the energy and labor required for cleaning and sterilization are eliminated. Set-up and changeover time (only 5–10 min for preparation) is minimal. A 500-L batch of animal cells is processed in about four hours. — GEA Group AG, Düsseldorf, Germany

www.gea.com

 

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