PAT Framework Provides Benefits in the CPI

Beyond product quality, process analytical technology (PAT) strategies optimize processes and efficiency in the chemical process industries The process analytical technology (PAT) initiative was started by the U.S. Food and Drug Administration (FDA) in 2003 to ensure quality of product in the pharmaceutical industry; however, many sectors of the chemical process industries (CPI) had already been incorporating similar strategies. Today’s advancements in analytical technologies and digitalization have taken these practices further, providing benefits in efficiency and optimization, as well as product quality and consistency. PAT provides an integrated framework that enables real-time measurement of the quality attributes of a product during the manufacturing process. Companies can steer and optimize these quality measurements via multivariate control of critical process parameters. While the framework reflects the concept that quality cannot be tested into a product but must be deployed throughout the life of the product, adopters found that, in addition to generating actionable insight into processes to enhance product quality and consistency, the in-depth understanding that this framework provides can create additional benefits.   Benefits…