Sartorius Stedim Biotech
SartoFlow Smart (photo) is a new benchtop crossflow system for optimized ultra- and diafiltration applications. It can be used in many downstream processes, such as purification of vaccines, monoclonal antibodies and recombinant proteins. The system is suitable for flexible use in laboratory environments for process development and clinical trials, as well as for cGMP environments. The system is equipped with a low-shear four-piston membrane pump that enables high product yields. In addition, the pump provides a wide range of flowrates, allowing users to choose membrane surface areas ranging from 50 cm² to 0.14 m². The crossflow system is supplied with the company’s DCU-4 control unit, which, when combined with the company’s BioPAT SCADA, MFCS-4 software, provides data logging and export capabilities. Its touchscreen offers instant access to all critical process parameters and displays control and alarm functions. A logbook function stores alarms, setpoints and user logs. — Sartorius Stedim Biotech, Aubagne, France