Producing chemicals and fuels by fermentation of renewable feedstocks can offer improved sustainability, lower costs and greater safety compared to conventional thermal processes. But realizing these benefits depends on a careful assessment of the process economics, and an understanding of…
Processes involving extremely low temperatures present unique process design and safety challenges. This one-page reference outlines considerations for low-temperature operations. Direct contact Extremely low temperatures can rapidly freeze human tissue. Contact between a worker’s bare skin and a low-temperature vapor,…
Adjustment and control of moisture levels in solid materials is a critical aspect in the manufacture of many chemical products. Drying can be defined as the vaporization and removal of water or other liquids from a solution, suspension, or other…
In hygienic process operations, proper system construction and fabrication has the greatest influence on end-product quality and the success of process validation. Even well-designed hygienic systems can be compromised by leaching, poor internal finishes and mishandled material sourcing and other…
A solid grasp of pump sizing allows engineers to make effective economic and practical decisions about process pumps. This one-page reference provides information about two key parameters and other considerations for pump sizing. Pump sizing steps Sizing a pump requires…
The ideal gas law ( PV = nRT), relating molar volume of a gas to pressure and temperature, is predicated on two assumptions: 1) that the volume occupied by the gas molecules is negligible compared to the volume of the…
Computer-generated simulations of distillation processes are often validated experimentally. This reference discusses three concepts that influence comparisons between experimental results and simulation predictions: vapor-liquid equilibrium (VLE) of the components; relative liquid-to-vapor flowrates (L/V ratios in the column); and vapor-liquid contactor…
Temperature measurement is critical in many types of process equipment, including reactors, distillation columns, furnaces, heat exchangers, evaporators, boilers and more. Among the most widely used instruments for measuring temperatures in chemical process industries (CPI) operations are resistance temperature detectors…
Designing a new solid-liquid filtration process or optimizing an existing one requires consideration of a number of factors aside from the type of filter that will be used. This one-page reference reviews two groups of considerations: one related to equipment,…
The kilogram is the last of the SI units (International System of Units) still defined by a physical object, rather than defined in terms of universal fundamental constants of nature. However, this will change in November 2018, as a multi-year…