Protect bioreactors from a variety of contaminants
MilliporeSigma
Viresolve Barrier capsule filters (photo) protect against bioreactor contamination by removing a range of viruses, mycoplasma and bacteria from cell-culture media. These barrier filters are designed to provide high-flux and high-capacity virus filtration and ensure desired productivity without impacting cell culture performance or protein quality attributes. For example, these capsule filters provide ≥ 3.0 log removal of parvovirus, ≥ 6.0 log removal of mycoplasma, and sterilizing-grade protection from bacteria, according to the manufacturer. They are scalable from bench-scale through commercial-scale operations. Used directly in front of the bioreactor, or in a media-storage container, they help to reduce process downtime, safeguard the downstream drug supply and ensure patient safety. This product is the latest in the company’s Viral Safety Assurance Program, which includes a variety of products and process solutions that prevent viruses from entering upstream processses, detect viruses in cells, raw materials and intermediates, and remove viruses in downstream processes. — MilliporeSigma, the Life Science business of Merck KGaA, Burlington, Mass.