Compound libraries are critical to pharmaceutical companies. Liquid handling for the dissolution of library compounds has been automated for many years, but the distribution and weighing of the original solid dry-stored library compound is still done manually. The Calli-L (photo) is specifically designed for the distribution of dry, powder library samples for dissolution, distributing samples directly from the original library vial without any additional preparation step. Calli-L is an automatic platform with a robotic arm supplied with a powder dispensing probe and a handler for transportation of vials in the range from less than 1 mg to 50 mg. The Calli-L uses an algorithm that chooses the best aspiration technique, and in combination with the balance, allows precise target weighing. The final target weight is documented with the container data (number, position on the container, time of distribution and so on) in the database. — Zinsser Analytic GmbH, Frankfurt am Main, Germany
