For the first time, perfusion disc separators for continuous production and faster processing can be implemented in biopharmaceutical cell-harvesting processes based on labor-saving, easy-to-use single-use devices. The newly introduced perfusion separators in this series (photo) offer the same advantages as classic disc separators for fed-batch processes. However, cleaning-in-place (CIP) and steam-in-place (SIP) cleaning is no longer necessary, meaning that the machine is ready for the next continuous process run in just a few minutes. In the kytero series, this company’s disc technology has been implemented in particularly compact machines with an easy-to-handle single-use separation unit that contains the entire disc pack. This separating unit and all associated feed and discharge lines are simply replaced after a production run, thus offering maximum convenience and protection against contamination. The kytero separators are available for the smallest setups, to variants as large as 500 and 2,000 L. — GEA AG, Düsseldorf, Germany